Polioforever's Blog

The Polio-like Diseases

In Humans…

Poisoning — lead, mercury, cyanide, arsenic, pesticides, etc.

Radiation – mining industry, x-rays, radium, fallout, medical scans and all known EM radiation sources (radar, tv, computers, cell phones, etc)

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Acute Flaccid Paralysis – The NIH reports the cause>>”Acute flaccid paralysis (AFP) can be caused by a number of conditions. A common preventable cause is poliomyelitis…Guillain Barre Syndrome (GBS), also known as Acute Inflammatory Demyelinating Polyneuropathy, is another common cause of acute flaccid paralysis” http://www.ncbi.nlm.nih.gov/pubmed/17867475

There are over 750 citations from pubmed;  http://www.ncbi.nlm.nih.gov/pubmed?term=acute%20flaccid%20paralysis&itool=QuerySuggestion ; typical medical citation from Taiwan indicating ‘enterovirus 71′ infection http://www.ajnr.org/cgi/content/full/22/1/200 ; AFP formerly known as polio http://www.uptodate.com/patients/content/topic.do?topicKey=~IUPB9AkEDWYcZ

…”The five main performance indicators for AFP surveillance cover completeness of reporting, sensitivity of surveillance, completeness of case investigation, completeness of follow up, and laboratory performance. As the eradication of poliomyelitis approaches in individual countries the criteria for its diagnosis become more stringent, relying more on virological than clinical classification”..http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=1227

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Meningitis - “Meningitis is an infection of the meninges, the thin lining that surrounds the brain and spinal cord. The most common causes of meningitis are viral and bacterial; fungal and parasitic infections are much less frequent. Before the 1990s, Haemophilus influenzae type b (Hib) was the leading cause of bacterial meningitis” http://www.meningvax.org/about-meningitis.php … “Enteroviruses circulate worldwide and are the most commonly identified cause of aseptic meningitis, particularly in infants and young children; 30,000–50,000 persons per year are hospitalized with aseptic meningitis in the United States”.. http://www.cdc.gov/NCIDOD/eid/vol11no04/04-0995.htm  The “enteric cytopathic human orphan” (echo)virus, isolated in the early 1950s is the most commonly found virus in meningitis http://www.answers.com/topic/echovirus

“A committee sponsored by the National Foundation for Infantile Paralysis categorized EVs [echoviruses] and other enteroviruses (ie, coxsackievirus group A and group B, polioviruses) together in 1957. They are grouped together and distinguished from other viruses on the basis of physicochemical characteristics and because they share common epidemiology, clinical manifestations, and pathogenesis.” http://emedicine.medscape.com/article/963458-overview

2009 – “Fears that a new epidemic wave may have started in Africa turn out to be true as 78,890 suspected cases and 4,243 deaths are reported during the epidemic season.”… ” The first mass vaccination campaigns will take place in 2010…  it is anticipated that the first round..will take place in late 2010 in Burkina Faso, followed by Mali and Niger.” http://www.meningvax.org/first-campaigns.php

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Encephalitis – brain infection, unrecognized as common to every case of polio until Johns Hopkins researcher David Bodian (Polio Hall of Fame) confirmed it in the late 1940s; http://www.time.com/time/magazine/article/0,9171,788210,00.html;  The “largest outbreak of arthropod-borne encephalitis in US history” was caused by West Nile Virus (1999-present, see below)

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Grippe/Influenza –  “The symptoms of milk sickness in man resemble those of influenza or grippe, gastritis, and so-called ptomaine poisoning. As a matter of fact, so-called summer grippe or flu occurs during epidemics of poliomyelitis. There were 10,000 cases in Cincinnati in 1947, which were thought to be related to poliomyelitis and were considered, therefore, virus infections.” –Dr. Ralph Scobey.  Albert Sabin proved that poliovirus induced grippe at the Children’s Hospital.

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Parkinson’s –  http://www.nlm.nih.gov/medlineplus/parkinsonsdisease.html ;   recognized by Leopold Ordenstein http://msj.sagepub.com/cgi/content/abstract/13/9/1195

The University of Chicago Medical Center reports>>”The cause (etiology) of Parkinson’s disease is unknown. It is very likely that more than one factor contribute to Parkinson’s disease” …”Epidemiological studies have noted increased risks of developing Parkinson’s disease with rural living, farming, drinking well water, and exposure to pesticides”   http://parkinsons.bsd.uchicago.edu/causes.html

A pesticide and industrial solvents cause is confirmed at this site http://www.thedailygreen.com/environmental-news/latest/tce-parkinsons-47010802

 Parkinson’s distribution from http://en.wikipedia.org/wiki/Parkinson’s_disease

“researchers at Rhode Island Hospital have found a substantial link from increased levels of nitrates in the environment to increased death from..Alzheimer’s and Parkinson’s.”  http://polioforever.wordpress.com/nitrogen/

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Multiple Sclerosis –  recently, experimental vascular surgery effectively cured an MS patient http://www.rebuildingyou.com/book-reviews/272-ms-new-experimental-treatment-ccsvi .  In 1977, an unusual ‘outbreak’ of MS occurred in Key West Florida : strange for appearing contagious and much farther south than is typical.  Here’s a larger world map of MS http://www.chumsweb.org/map.htm. The  map shows a very strong fallout correlation. MS, Chronic Fatigue, Epstein-Barr virus infection and AIDS all began a parallel surge in the late ’70s, peaking in 1985.

This is what the NIH says about MS >>”No one knows what causes MS. It may be an autoimmune disease, which happens when your body attacks itself. Multiple sclerosis affects women more than men. It often begins between the ages of 20 and 40. Usually, the disease is mild, but some people lose the ability to write, speak or walk. There is no cure for MS, but medicines may slow it down and help control symptoms” http://www.nlm.nih.gov/medlineplus/multiplesclerosis.html

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Amytrophic Lateral Sclerosis (ALS), Lou Gehrig’s or Charcot’s Disease – citations http://www.neurology.org/cgi/collection/anterior_nerve_cell_disease?page=1; the role of glutamates (neurotransmitter glutamic acid) http://www.als.net.articles/articleDetail.asp?articleID=5146

The NIH says >>” Most people with amyotrophic lateral sclerosis have a form of the condition that is described as sporadic or noninherited. The cause of sporadic amyotrophic lateral sclerosis is largely unknown but probably involves a combination of genetic and environmental factors.” http://ghr.nlm.nih.gov/condition=amyotrophiclateralsclerosis

http://www.aafp.org/afp/990315ap/1489.html  “Pathology — Atrophy of the anterior horn cells and replacement of the large motor neurons by fibrous astrocytes (gliosis) causes the affected anterior and lateral columns of the spinal cord to become hard, hence the term “lateral sclerosis.”4 Large neurons tend to be affected before small ones…In the brain, atrophic changes may be found in the motor and premotor cortex.4,7 Peripheral nerves show secondary degeneration of axons and myelin.

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Lupushttp://www.csmc.edu/5567.html

The NIH says >>”The cause of lupus is not known. Research suggests that genes play an important role, but genes alone do not determine who gets lupus. It is likely that many factors trigger the disease.” http://www.niams.nih.gov/Health_Info/Lupus/lupus_ff.asp

Gary Matsumoto wrote in a GWS/anthrax forum that “Rachael Lacy – who died after anthrax immunization at Fort McCoy, Wisconsin – received shots from anthrax vaccine lot number FAV 073. The autopsy report from the Mayo Clinic (where she died) said Lacy had a “lupus-like illness.” http://www.hspig.org/MT/weblogs-hspig/archives/2004/11/anthrax_vaccine.html

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Myalgic Encephalomyelitis –  “The name myalgic encephalomyelitis (ME) was coined in the 1950s to clarify well-documented outbreaks of disease; however, ME is accompanied by neurologic and muscular signs and has a case definition distinct from that of CFS.” http://myalgic-encephalomyelitis.com/ ME patients ” are at times disablingly intolerant of sensory stimuli, have markedly reduced tolerance for alcohol, medicines and various food stuffs, with disturbances in autonomous,  hormonal, neurological and immunological functions, disturbed body clock, and pains which are not relieved by treatment. In a fully developed illness there are symptoms from all organs and bodily systems. Symptomology is constantly changing. Lack of explanation for a cause gives rise to psychiatric interpretations. Recent studies, however, show changes in the peripheral circulation…” http://www.investinme.org/Article-244%20Kreyberg%20Caring%20for%20seriously%20ill%20ME-patients.htm

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Chronic Fatigue Syndrome http://www.answers.com/topic/chronic-fatigue-syndrome ; CFS is the subject of journalist Hillary Johnson’s book “Osler’s Web” which opens with the events of “Tahoe Flu” and the common finding of Chronic Epstein-Barr Virus infection. Thought to be a retroviral disease, the syndrome is less fatal than AIDS but appears to leave its victims with greater neurological deficits; studies over time revealed Epstein-Barr virus, Human Herpes Virus 6, Simian Cytomegalovirus (SCMV, an ‘atypical herpes simplex encephalitis) and Human Lymphotropic T-cell Virus. Patients reported their illness began with the flu from which they never recovered. Newsweek magazine , 1990 http://www.newsweek.com/id/128028/page/1  offers a brief on the investigation of Tahoe flu. In Hillary Johnson’s 1996 book, CFS patients eerily engaged their physicians with the news that “they felt as if they had been poisoned or were experiencing something akin to radiation sickness”; page 71, Osler’s Web. MRI Brain scans revealed many of these patients had “punctate lesions”.

Dr. Elizabeth Dowsett – says CFS “strikes one clinically as being polio-like and it has often been diagnosed as ‘nonparalytic polio’ “

Dr. Bill Douglass  – “The evidence is fairly convincing that Gulf War Syndrome is..vaccination-induced chronic fatigue syndrome….Salk and Sabin opened Pandora’s Box and we now have 72 types of polio rather than three” [for the 72 enterovirus types?] http://www.whale.to/vaccines/douglass.html

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Guillain-Barre – “Guillain Barre Syndrome ia an acute inflammatory demyelinating polyneuropathy”.. http://www.ayubmed.edu.pk/JAMC/PAST/19-1/07%20Anisur%20Rehman.pdf; “Fatigue, pain and muscle weakness are frequent after Guillain-Barre syndrome and poliomyelitis.” http://lib.bioinfo.pl/auid:2178917 (citation by Tiina Rekand, Univ. of Bergen, Norway)

According to the NIH>>”No one yet knows why Guillain-Barré—which is not contagious—strikes some people and not others. Nor does anyone know exactly what sets the disease in motion.” http://www.ninds.nih.gov/disorders/gbs/detail_gbs.htm

Porphyria: “…the polyneuropathy of acute porphyria may be mistaken for Guillain-Barré syndrome, and porphyria testing is commonly recommended in those situations.[5] Systemic lupus erythematosus features photosensitivity and pain attacks and shares various other symptoms with porphyria… Patients with acute porphyria (AIP, HCP, VP) are at increased risk over their life for hepatocellular carcinoma (primary liver cancer)… In humans, porphyrins are the main precursors of heme, an essential constituent of hemoglobin, myoglobin, catalase, peroxidase, respiratory and P450 liver cytochromes… There are eight enzymes in the heme biosynthetic pathway, four of which—the first one and the last three—are in the mitochondria, while the other four are in the cytosol. Defects in any of these can lead to some form of porphyria.” http://en.wikipedia.org/wiki/Porphyria

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Fibromyalgia –  from the NIH>>”The causes of fibromyalgia are unknown. There may be a number of factors involved.” http://www.niams.nih.gov/Health_Info/Fibromyalgia/fibromyalgia_ff.asp

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Alzheimer’s - The NIH maintains “Scientists don’t yet fully understand what causes AD, but it is clear that it develops because of a complex series of events that take place in the brain over a long period of time.” http://www.nia.nih.gov/Alzheimers/AlzheimersInformation/Causes/

“A small but growing chorus of scientists is becoming convinced that insulin is just as important to the brain as it is to the body:…When brain cells are deprived of insulin, they die.
…Dr. Suzanne de la Monte, a neuropathologist at Rhode Island Hospital in Providence, believes that Alzheimer’s Disease could be called ‘Type 3 diabetes’…”

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Creutzfeld-Jacob Diseasehttp://www.ninds.nih.gov/disorders/cjd/detail_cjd.htm

“CJD is believed to result from a protein called a prion. A prion causes normal proteins to fold abnormally. This affects the other proteins’ ability to function. There are several types of CJD.  Classic CJD is not related to mad cow disease (bovine spongiform encephalitis). However, new variant CJD (nvCJD) is an infectious form that is”…”CJD is rarely confused with other types of dementia (such as Alzheimer’s disease) because in CJD, symptoms progress much more rapidly. Both forms of CJD are distinguished by extremely rapid progression from onset of symptoms to disability and death.”   http://www.nlm.nih.gov/medlineplus/ency/article/000788.htm

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West Nile Virus infection – identical pathology to polio http://www.cdc.gov/ncidod/eid/vol9no7/03-0129.htm; ‘discovered’ in 1937 Africa in a human patient http://outlook.wustl.edu/winter2002/westnile.html; neuroinvasive Israeli strain in U.S. West Nile cases  – “After the virus struck New York, Israeli researchers learned the strain that infected the fowl was “almost identical” to the New York virus  http://www.nydailynews.com/archives/news/1999/11/22/1999-11-22_israel_on_virus_attack__will.html,   http://www.ncbi.nlm.nih.gov/pmc/articles/PMC535539/ .  Managment of the official response to the New York West Nile Virus outbreak went to Jerome Hauer who initiated a spraying campaign and is involved in the 9-11 WTC attack as the man who facilitated John O’Neill’s new job on Sept.10, worked for WTC security Kroll, and designed the City’s WTC7 ‘Command Post’. Here is an overview of how West Nile spread across the US from “ground zero” in Central Park http://citizen2009.wordpress.com/west-nile-virus/;  http://en.wikipedia.org/wiki/Progress_of_the_West_Nile_virus_in_the_United_States

” The virus was first discovered in the West Nile District of Uganda in 1937.  In 1957, West Nile virus was recognized as the cause of severe inflammation of the brain and spinal column in infected elderly patients in Israel.”…http://www.abramsroyalpharmacy.com/html/west_nile_virus.html …”In 2007, WNV caused 3,404 cases of disease in the United States, including 98 deaths, according to the Centers for Disease Control and Prevention (CDC).” http://www3.niaid.nih.gov/topics/westNile/understanding/what.htm

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Enterovirus 71 infection – http://www.vadscorner.com/enterostudy.html; “Poliovirus and enterovirus 71 (EV71) are neurotropic human enteroviruses… The major neurological manifestation of severe poliovirus infection is paralytic poliomyelitis. In contrast, recent and historical EV71 epidemics throughout the world have demonstrated a wider variety of clinical manifestations, ranging from the mild HFMD to fatal encephalitis and acute flaccid paralysis (Schmidt et al., 1974; Chumakov et al., 1979; Melnick, 1984; Ho et al., 1999; Chan et al., 2000).”  http://vir.sgmjournals.org/content/85/10/2981.full

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Psychological Illness

Neuropsychiatric Illness

Post-Polio Syndrome

Foot Drop http://en.wikipedia.org/wiki/Foot_drop

“Polio feet” http://www.newmobility.com/articleViewIE.cfm?id=340

Vitamin B-12 Deficiency – CNS wasting; bone marrow disorders; pernicious anemia

Human Adjuvant Disease (HAD) and Gulf War Syndrome http://www.gulflink.osd.mil/finalrpt.html

Cancer – (SV40, vaccine induced, general infection) “Cellular viability and propagation require that genomes be reasonably stable. Cancer is an example of a genetic disease often associated with and, in some cases, perhaps engendered by the loss of genomic stability….DNA motifs that are predisposed to genetic change have been referred to as at-risk motifs. A long inverted repeat (LIR)..is an example of an at-risk motif. “… http://www.genetics.org/cgi/content/full/153/4/1873

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In Animals – these are categories of related illnesses

Mad Cow, bovine spongiform encephalopathy http://citizen2009.wordpress.com/mad-cow-mad-people/

atypical porcine enterovirus encephalomyelitis

bovine polioencephalomalacia

polyradiculoneuritis

poliomyelomalacia

In Insects

Israeli Acute Paralysis Virus in Colony Collapse Disorder http://citizen2009.wordpress.com/2009/11/22/colony-collapse-disorder-bees-knees-and-polio/

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Neurosurgeon Dr. Russell Blaylock speaks on the “Chemical Dumbing Down of Society” http://www.youtube.com/watch?v=dAEwGqd12cs

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Neurology Citations :

http://www.neurology.org/collections/index.dtl#demyelinating_disease_cns

http://www.neurology.org/collections/index.dtl#epidemiology

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http://www.alzforum.org/new/detail.asp?id=2239

19 September 2009. As amyotrophic lateral sclerosis ravages motor neurons, causing paralysis, the immune system does not sit idly by. It sends out its troops to battle the internal threat—but some of those same soldiers may also turn against the neurons they were sent to protect. In the past few years, most attention has focused on the role of innate immunity in ALS: microglia, the nervous system’s resident immune representatives, can both assist and harm motor neurons depending on the circumstances (see ARF News story). Now, scientists have noticed that the adaptive side of the immune system, too, gets into the act in ALS and other neurodegenerative diseases. But the adaptive immune system may also fall victim to the disease, as a handful of papers show diminished immune responses in animal models as well as in people with ALS. “It is becoming a hot-button issue,” said Howard Gendelman of the University of Nebraska Medical Center in Omaha. “It is a new paradigm to look at these diseases.”The most recent bit of evidence tying adaptive immunity to ALS comes from the laboratory of Michal Schwartz at the Weizmann Institute of Science in Rehovot, Israel (Seksenyan et al., 2009). T cells are born in the bone marrow and migrate to the thymus, where they undergo a maturation that involves rearranging their gene for the antigen receptor and discarding the DNA that is no longer necessary. Those waste bits remain in cells circulating in the bloodstream and serve as markers for mature T cells. The Israeli scientists reported that there were fewer such remnants in the blood of people with ALS, suggesting that fewer T cells were reaching maturity. The blood cells of people with ALS also showed reduced activity in key immune genes. In three people with ALS who underwent MRI or X-ray, Schwartz and colleagues found that the thymus was essentially gone; the chunk of tissue in its place lacked the organ’s characteristic layered texture. “The ALS patient shows an immune system like an 80-year-old,” Schwartz said.The most common animal model for ALS is based on the fact that in one fifth of familial ALS cases, the person possesses a mutant form of superoxide dismutase 1 (SOD1). ALS model mice overexpressing human mutant SOD1 also show evidence of reduced immune function. Even before the animals exhibited motor neuron symptoms, Schwartz and colleagues found thymic abnormalities including fewer T cell progenitors. In this and a previous study by another group, researchers have shown that the spleen of mSOD1 mice is reduced in size and lymphocyte numbers, as well (Banerjee et al., 2008 ).Two-Faced T Cells
Schwartz has been promoting the positive role of adaptive immunity in nervous system maintenance and repair since the late 1990s, when she and colleagues showed that macrophages and T cells are involved in injury repair in the CNS (Rapalino et al., 1998 ; Moalem et al., 1999). “The community thought that we were crazy,” she said. The conventional wisdom was that the brain and spinal cord were separated from immune cells by the blood-brain barrier, and that any immune cells infiltrating the central nervous system must be evidence of a pathologically leaking barrier.A trio of recent publications from three different labs supports Schwartz’s ideas in the case of ALS. A few years back, Schwartz said, she suggested to Stanley Appel of the Methodist Hospital System in Houston, Texas, that he make ALS mice devoid of T cells. When he and colleagues crossed mSOD1 mice with a strain lacking functional T cells, the progeny sickened faster. Bone marrow transplants that produced T cells reversed the effect (see ARF News story on Beers et al., 2008).Similarly, researchers led by Isaac Chiu in the Harvard Medical School lab of Michael Carroll in Boston, Massachusetts, crossed mSOD1 mice with animals deficient in T cell receptors. The progeny showed accelerated ALS disease (Chiu et al., 2008). In another report, Gendelman and colleagues also found evidence that T cells fight ALS, showing that providing activated T cells to mSOD1 animals delayed the onset of symptoms and slowed disease progression (Banerjee et al., 2008 ).This role for the immune system in ALS is one of amplification, Appel said, and is distinct from pathological autoimmunity in diseases such as multiple sclerosis or lupus. Schwartz has proposed that long before noticeable symptoms of ALS appear, the immune system is busily protecting the neurons (Schwartz and Ziv, 2008): T cells flow to damaged or ailing areas to manage the healing process, dampen inflammation, or prevent cell death. But at some point, the disease overwhelms the immune system. “The onset will be when you pass the threshold between what the immune system can provide and what the central nervous system needs,” she said. Similarly, the immune system battles tumor cells, but when it can no longer withstand them, cancer develops. The same could be true for other neurodegenerative diseases, Schwartz suggested. In the case of Alzheimer disease, the symptoms may appear as the aging immune system can no longer hold the pathology in check.

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